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Dendritic cell derived exosomes loaded with immunoregulatory cargo reprogram local immune responses and inhibit degenerative bone disease in vivo
Chronic bone degenerative diseases represent a major threat to the health and well-being of the population, particularly those with advanced age. This study isolated exosomes (EXO), natural nano-particles, from dendritic cells, the “directors” of the immune response, to examine the immunobiology of...
Autores principales: | Elashiry, Mahmoud, Elashiry, Mohamed M., Elsayed, Ranya, Rajendran, Mythily, Auersvald, Carol, Zeitoun, Rana, Rashid, Mohammad H., Ara, Roxan, Meghil, Mohamed M., Liu, Yutao, Arbab, Ali S., Arce, Roger M., Hamrick, Mark, Elsalanty, Mohammed, Brendan, Marshall, Pacholczyk, Rafal, Cutler, Christopher W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480413/ https://www.ncbi.nlm.nih.gov/pubmed/32944183 http://dx.doi.org/10.1080/20013078.2020.1795362 |
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