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Making waves: Wastewater-based epidemiology for COVID-19 – approaches and challenges for surveillance and prediction

The presence of SARS-CoV-2 in the feces of infected patients and wastewater has drawn attention, not only to the possibility of fecal-oral transmission but also to the use of wastewater as an epidemiological tool. The COVID-19 pandemic has highlighted problems in evaluating the epidemiological scope...

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Detalles Bibliográficos
Autores principales: Polo, David, Quintela-Baluja, Marcos, Corbishley, Alexander, Jones, Davey L., Singer, Andrew C., Graham, David W., Romalde, Jesús L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480445/
https://www.ncbi.nlm.nih.gov/pubmed/32942178
http://dx.doi.org/10.1016/j.watres.2020.116404
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author Polo, David
Quintela-Baluja, Marcos
Corbishley, Alexander
Jones, Davey L.
Singer, Andrew C.
Graham, David W.
Romalde, Jesús L.
author_facet Polo, David
Quintela-Baluja, Marcos
Corbishley, Alexander
Jones, Davey L.
Singer, Andrew C.
Graham, David W.
Romalde, Jesús L.
author_sort Polo, David
collection PubMed
description The presence of SARS-CoV-2 in the feces of infected patients and wastewater has drawn attention, not only to the possibility of fecal-oral transmission but also to the use of wastewater as an epidemiological tool. The COVID-19 pandemic has highlighted problems in evaluating the epidemiological scope of the disease using classical surveillance approaches, due to a lack of diagnostic capacity, and their application to only a small proportion of the population. As in previous pandemics, statistics, particularly the proportion of the population infected, are believed to be widely underestimated. Furthermore, analysis of only clinical samples cannot predict outbreaks in a timely manner or easily capture asymptomatic carriers. Threfore, community-scale surveillance, including wastewater-based epidemiology, can bridge the broader community and the clinic, becoming a valuable indirect epidemiological prediction tool for SARS-CoV-2 and other pandemic viruses. This article summarizes current knowledge and discusses the critical factors for implementing wastewater-based epidemiology of COVID-19.
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spelling pubmed-74804452020-09-09 Making waves: Wastewater-based epidemiology for COVID-19 – approaches and challenges for surveillance and prediction Polo, David Quintela-Baluja, Marcos Corbishley, Alexander Jones, Davey L. Singer, Andrew C. Graham, David W. Romalde, Jesús L. Water Res Article The presence of SARS-CoV-2 in the feces of infected patients and wastewater has drawn attention, not only to the possibility of fecal-oral transmission but also to the use of wastewater as an epidemiological tool. The COVID-19 pandemic has highlighted problems in evaluating the epidemiological scope of the disease using classical surveillance approaches, due to a lack of diagnostic capacity, and their application to only a small proportion of the population. As in previous pandemics, statistics, particularly the proportion of the population infected, are believed to be widely underestimated. Furthermore, analysis of only clinical samples cannot predict outbreaks in a timely manner or easily capture asymptomatic carriers. Threfore, community-scale surveillance, including wastewater-based epidemiology, can bridge the broader community and the clinic, becoming a valuable indirect epidemiological prediction tool for SARS-CoV-2 and other pandemic viruses. This article summarizes current knowledge and discusses the critical factors for implementing wastewater-based epidemiology of COVID-19. The Authors. Published by Elsevier Ltd. 2020-11-01 2020-09-09 /pmc/articles/PMC7480445/ /pubmed/32942178 http://dx.doi.org/10.1016/j.watres.2020.116404 Text en © 2020 The Authors. Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Polo, David
Quintela-Baluja, Marcos
Corbishley, Alexander
Jones, Davey L.
Singer, Andrew C.
Graham, David W.
Romalde, Jesús L.
Making waves: Wastewater-based epidemiology for COVID-19 – approaches and challenges for surveillance and prediction
title Making waves: Wastewater-based epidemiology for COVID-19 – approaches and challenges for surveillance and prediction
title_full Making waves: Wastewater-based epidemiology for COVID-19 – approaches and challenges for surveillance and prediction
title_fullStr Making waves: Wastewater-based epidemiology for COVID-19 – approaches and challenges for surveillance and prediction
title_full_unstemmed Making waves: Wastewater-based epidemiology for COVID-19 – approaches and challenges for surveillance and prediction
title_short Making waves: Wastewater-based epidemiology for COVID-19 – approaches and challenges for surveillance and prediction
title_sort making waves: wastewater-based epidemiology for covid-19 – approaches and challenges for surveillance and prediction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480445/
https://www.ncbi.nlm.nih.gov/pubmed/32942178
http://dx.doi.org/10.1016/j.watres.2020.116404
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