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Generation of reactive oxygen species by hydroxypyridone compound/iron complexes

Objectives: Prooxidant properties of iron-binding hydroxypyridone compounds including deferiprone and mimosine were analyzed. Methods: Hydroxypyridone/iron-dependent production of reactive oxygen species was evidenced by the inactivation of aconitase, the most sensitive enzyme to oxidative stress in...

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Detalles Bibliográficos
Autores principales:	Murakami, Keiko, Yoshino, Masataka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480593/ https://www.ncbi.nlm.nih.gov/pubmed/32615878 http://dx.doi.org/10.1080/13510002.2020.1787662

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