Potential use of polyphenols in the battle against COVID-19

The coronavirus disease 2019 (COVID-19) is a public health emergency of international concern. The rising number of cases of this highly transmissible infection has stressed the urgent need to find a potent drug. Although repurposing of known drugs currently provides an accelerated route to approval...

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Detalles Bibliográficos
Autores principales: Paraiso, Ines L, Revel, Johana S, Stevens, Jan F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480644/
https://www.ncbi.nlm.nih.gov/pubmed/32923374
http://dx.doi.org/10.1016/j.cofs.2020.08.004
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author Paraiso, Ines L
Revel, Johana S
Stevens, Jan F
author_facet Paraiso, Ines L
Revel, Johana S
Stevens, Jan F
author_sort Paraiso, Ines L
collection PubMed
description The coronavirus disease 2019 (COVID-19) is a public health emergency of international concern. The rising number of cases of this highly transmissible infection has stressed the urgent need to find a potent drug. Although repurposing of known drugs currently provides an accelerated route to approval, there is no satisfactory treatment. Polyphenols, a major class of bioactive compounds in nature, are known for their antiviral activity and pleiotropic effects. The aim of this review is to assess the effects of polyphenols on COVID-19 drug targets as well as to provide a perspective on the possibility to use polyphenols in the development of natural approaches against this viral disease.
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spelling pubmed-74806442020-09-09 Potential use of polyphenols in the battle against COVID-19 Paraiso, Ines L Revel, Johana S Stevens, Jan F Curr Opin Food Sci Article The coronavirus disease 2019 (COVID-19) is a public health emergency of international concern. The rising number of cases of this highly transmissible infection has stressed the urgent need to find a potent drug. Although repurposing of known drugs currently provides an accelerated route to approval, there is no satisfactory treatment. Polyphenols, a major class of bioactive compounds in nature, are known for their antiviral activity and pleiotropic effects. The aim of this review is to assess the effects of polyphenols on COVID-19 drug targets as well as to provide a perspective on the possibility to use polyphenols in the development of natural approaches against this viral disease. The Authors. Published by Elsevier Ltd. 2020-04 2020-09-09 /pmc/articles/PMC7480644/ /pubmed/32923374 http://dx.doi.org/10.1016/j.cofs.2020.08.004 Text en © 2020 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Paraiso, Ines L
Revel, Johana S
Stevens, Jan F
Potential use of polyphenols in the battle against COVID-19
title Potential use of polyphenols in the battle against COVID-19
title_full Potential use of polyphenols in the battle against COVID-19
title_fullStr Potential use of polyphenols in the battle against COVID-19
title_full_unstemmed Potential use of polyphenols in the battle against COVID-19
title_short Potential use of polyphenols in the battle against COVID-19
title_sort potential use of polyphenols in the battle against covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480644/
https://www.ncbi.nlm.nih.gov/pubmed/32923374
http://dx.doi.org/10.1016/j.cofs.2020.08.004
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