Epithelial organ shape is generated by patterned actomyosin contractility and maintained by the extracellular matrix

Epithelial sheets define organ architecture during development. Here, we employed an iterative multiscale computational modeling and quantitative experimental approach to decouple direct and indirect effects of actomyosin-generated forces, nuclear positioning, extracellular matrix, and cell-cell adh...

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Detalles Bibliográficos
Autores principales: Nematbakhsh, Ali, Levis, Megan, Kumar, Nilay, Chen, Weitao, Zartman, Jeremiah J., Alber, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480841/
https://www.ncbi.nlm.nih.gov/pubmed/32817654
http://dx.doi.org/10.1371/journal.pcbi.1008105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480841/
https://www.ncbi.nlm.nih.gov/pubmed/32817654
http://dx.doi.org/10.1371/journal.pcbi.1008105

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