Cargando…
Epithelial organ shape is generated by patterned actomyosin contractility and maintained by the extracellular matrix
Epithelial sheets define organ architecture during development. Here, we employed an iterative multiscale computational modeling and quantitative experimental approach to decouple direct and indirect effects of actomyosin-generated forces, nuclear positioning, extracellular matrix, and cell-cell adh...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480841/ https://www.ncbi.nlm.nih.gov/pubmed/32817654 http://dx.doi.org/10.1371/journal.pcbi.1008105 |