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Lyssavirus P-protein selectively targets STAT3-STAT1 heterodimers to modulate cytokine signalling

Many viruses target signal transducer and activator of transcription (STAT) 1 to antagonise antiviral interferon signalling, but targeting of STAT3, a pleiotropic molecule that mediates signalling by diverse cytokines, is poorly understood. Here, using lyssavirus infection, quantitative live cell im...

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Detalles Bibliográficos
Autores principales: Harrison, Angela R., Lieu, Kim G., Larrous, Florence, Ito, Naoto, Bourhy, Hervé, Moseley, Gregory W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480851/
https://www.ncbi.nlm.nih.gov/pubmed/32903273
http://dx.doi.org/10.1371/journal.ppat.1008767