Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5

Host resistance to Toxoplasma gondii relies on CD8 T cell IFNγ responses, which if modulated by the host or parasite could influence chronic infection and parasite transmission between hosts. Since host-parasite interactions that govern this response are not fully elucidated, we investigated require...

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Detalles Bibliográficos
Autores principales: Kongsomboonvech, Angel K., Rodriguez, Felipe, Diep, Anh L., Justice, Brandon M., Castallanos, Brayan E., Camejo, Ana, Mukhopadhyay, Debanjan, Taylor, Gregory A., Yamamoto, Masahiro, Saeij, Jeroen P. J., Reese, Michael L., Jensen, Kirk D. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480859/
https://www.ncbi.nlm.nih.gov/pubmed/32853276
http://dx.doi.org/10.1371/journal.ppat.1008327

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