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Assessment of transcriptomic constraint-based methods for central carbon flux inference

MOTIVATION: Determining intracellular metabolic flux through isotope labeling techniques such as (13)C metabolic flux analysis ((13)C-MFA) incurs significant cost and effort. Previous studies have shown transcriptomic data coupled with constraint-based metabolic modeling can determine intracellular...

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Detalles Bibliográficos
Autores principales:	Bhadra-Lobo, Siddharth, Kim, Min Kyung, Lun, Desmond S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480874/ https://www.ncbi.nlm.nih.gov/pubmed/32903284 http://dx.doi.org/10.1371/journal.pone.0238689

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