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Large Bowel Obstruction in the Setting of Small Lymphocytic Lymphoma

Large bowel obstruction (LBO) is a potential surgical emergency, commonly caused by colorectal carcinoma, diverticular stricture, and volvulus. LBO secondary to chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) is a rare occurrence. We report an 81-year-old man with a history o...

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Autores principales: Cheng, Abigail W, Abdeljaber, Mahmuod, Lima, Neiberg A, Shebrain, Saad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480891/
https://www.ncbi.nlm.nih.gov/pubmed/32923240
http://dx.doi.org/10.7759/cureus.9640
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author Cheng, Abigail W
Abdeljaber, Mahmuod
Lima, Neiberg A
Shebrain, Saad
author_facet Cheng, Abigail W
Abdeljaber, Mahmuod
Lima, Neiberg A
Shebrain, Saad
author_sort Cheng, Abigail W
collection PubMed
description Large bowel obstruction (LBO) is a potential surgical emergency, commonly caused by colorectal carcinoma, diverticular stricture, and volvulus. LBO secondary to chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) is a rare occurrence. We report an 81-year-old man with a history of CLL/SLL who presented to the emergency department with episodes of abdominal cramps and discomfort, diarrhea, vomiting, subjective flushes, and sweats. After a thorough evaluation, the patient was found to have a malignancy-mediated mechanical LBO at the hepatic flexure due to colonic compression by extensive pericolic lymphadenopathy. After resuscitation and medical optimization, an urgent laparotomy with oncologic right hemicolectomy was performed. Analysis of resected specimens, including lymph nodes, revealed atypical CD23- CLL/SLL cells. Postoperatively, aside from temporary ileus, the patient recovered well and was discharged home.
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spelling pubmed-74808912020-09-11 Large Bowel Obstruction in the Setting of Small Lymphocytic Lymphoma Cheng, Abigail W Abdeljaber, Mahmuod Lima, Neiberg A Shebrain, Saad Cureus General Surgery Large bowel obstruction (LBO) is a potential surgical emergency, commonly caused by colorectal carcinoma, diverticular stricture, and volvulus. LBO secondary to chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) is a rare occurrence. We report an 81-year-old man with a history of CLL/SLL who presented to the emergency department with episodes of abdominal cramps and discomfort, diarrhea, vomiting, subjective flushes, and sweats. After a thorough evaluation, the patient was found to have a malignancy-mediated mechanical LBO at the hepatic flexure due to colonic compression by extensive pericolic lymphadenopathy. After resuscitation and medical optimization, an urgent laparotomy with oncologic right hemicolectomy was performed. Analysis of resected specimens, including lymph nodes, revealed atypical CD23- CLL/SLL cells. Postoperatively, aside from temporary ileus, the patient recovered well and was discharged home. Cureus 2020-08-10 /pmc/articles/PMC7480891/ /pubmed/32923240 http://dx.doi.org/10.7759/cureus.9640 Text en Copyright © 2020, Cheng et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle General Surgery
Cheng, Abigail W
Abdeljaber, Mahmuod
Lima, Neiberg A
Shebrain, Saad
Large Bowel Obstruction in the Setting of Small Lymphocytic Lymphoma
title Large Bowel Obstruction in the Setting of Small Lymphocytic Lymphoma
title_full Large Bowel Obstruction in the Setting of Small Lymphocytic Lymphoma
title_fullStr Large Bowel Obstruction in the Setting of Small Lymphocytic Lymphoma
title_full_unstemmed Large Bowel Obstruction in the Setting of Small Lymphocytic Lymphoma
title_short Large Bowel Obstruction in the Setting of Small Lymphocytic Lymphoma
title_sort large bowel obstruction in the setting of small lymphocytic lymphoma
topic General Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480891/
https://www.ncbi.nlm.nih.gov/pubmed/32923240
http://dx.doi.org/10.7759/cureus.9640
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