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Speciation and the developmental alarm clock

New species arise as the genomes of populations diverge. The developmental ‘alarm clock’ of speciation sounds off when sufficient divergence in genetic control of development leads hybrid individuals to infertility or inviability, the world awoken to the dawn of new species with intrinsic post-zygot...

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Detalles Bibliográficos
Autores principales: Cutter, Asher D, Bundus, Joanna D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481004/
https://www.ncbi.nlm.nih.gov/pubmed/32902377
http://dx.doi.org/10.7554/eLife.56276
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author Cutter, Asher D
Bundus, Joanna D
author_facet Cutter, Asher D
Bundus, Joanna D
author_sort Cutter, Asher D
collection PubMed
description New species arise as the genomes of populations diverge. The developmental ‘alarm clock’ of speciation sounds off when sufficient divergence in genetic control of development leads hybrid individuals to infertility or inviability, the world awoken to the dawn of new species with intrinsic post-zygotic reproductive isolation. Some developmental stages will be more prone to hybrid dysfunction due to how molecular evolution interacts with the ontogenetic timing of gene expression. Considering the ontogeny of hybrid incompatibilities provides a profitable connection between ‘evo-devo’ and speciation genetics to better link macroevolutionary pattern, microevolutionary process, and molecular mechanisms. Here, we explore speciation alongside development, emphasizing their mutual dependence on genetic network features, fitness landscapes, and developmental system drift. We assess models for how ontogenetic timing of reproductive isolation can be predictable. Experiments and theory within this synthetic perspective can help identify new rules of speciation as well as rules in the molecular evolution of development.
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spelling pubmed-74810042020-09-11 Speciation and the developmental alarm clock Cutter, Asher D Bundus, Joanna D eLife Developmental Biology New species arise as the genomes of populations diverge. The developmental ‘alarm clock’ of speciation sounds off when sufficient divergence in genetic control of development leads hybrid individuals to infertility or inviability, the world awoken to the dawn of new species with intrinsic post-zygotic reproductive isolation. Some developmental stages will be more prone to hybrid dysfunction due to how molecular evolution interacts with the ontogenetic timing of gene expression. Considering the ontogeny of hybrid incompatibilities provides a profitable connection between ‘evo-devo’ and speciation genetics to better link macroevolutionary pattern, microevolutionary process, and molecular mechanisms. Here, we explore speciation alongside development, emphasizing their mutual dependence on genetic network features, fitness landscapes, and developmental system drift. We assess models for how ontogenetic timing of reproductive isolation can be predictable. Experiments and theory within this synthetic perspective can help identify new rules of speciation as well as rules in the molecular evolution of development. eLife Sciences Publications, Ltd 2020-09-09 /pmc/articles/PMC7481004/ /pubmed/32902377 http://dx.doi.org/10.7554/eLife.56276 Text en © 2020, Cutter and Bundus http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Developmental Biology
Cutter, Asher D
Bundus, Joanna D
Speciation and the developmental alarm clock
title Speciation and the developmental alarm clock
title_full Speciation and the developmental alarm clock
title_fullStr Speciation and the developmental alarm clock
title_full_unstemmed Speciation and the developmental alarm clock
title_short Speciation and the developmental alarm clock
title_sort speciation and the developmental alarm clock
topic Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481004/
https://www.ncbi.nlm.nih.gov/pubmed/32902377
http://dx.doi.org/10.7554/eLife.56276
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