Cargando…
A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development
During the development of the cerebral cortex, neurons are generated directly from radial glial cells or indirectly via basal progenitors. The balance between these division modes determines the number and types of neurons formed in the cortex thereby affecting cortical functioning. Here, we investi...
Autores principales: | Hasenpusch-Theil, Kerstin, Laclef, Christine, Colligan, Matt, Fitzgerald, Eamon, Howe, Katherine, Carroll, Emily, Abrams, Shaun R, Reiter, Jeremy F, Schneider-Maunoury, Sylvie, Theil, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481005/ https://www.ncbi.nlm.nih.gov/pubmed/32840212 http://dx.doi.org/10.7554/eLife.58162 |
Ejemplares similares
-
Forebrain development in the Inpp5e ciliary mouse mutant is severely disrupted
por: Theil, T, et al.
Publicado: (2012) -
The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling
por: Schembs, Leah, et al.
Publicado: (2022) -
The Multifaceted Roles of Primary Cilia in the Development of the Cerebral Cortex
por: Hasenpusch-Theil, Kerstin, et al.
Publicado: (2021) -
Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through Cdk6 expression
por: Hasenpusch-Theil, Kerstin, et al.
Publicado: (2018) -
Multiple ciliary localization signals control INPP5E ciliary targeting
por: Cilleros-Rodriguez, Dario, et al.
Publicado: (2022)