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Functional regulation of an ancestral RAG transposon ProtoRAG by a trans-acting factor YY1 in lancelet
The discovery of ancestral RAG transposons in early deuterostomia reveals the origin of vertebrate V(D)J recombination. Here, we analyze the functional regulation of a RAG transposon, ProtoRAG, in lancelet. We find that a specific interaction between the cis-acting element within the TIR sequences o...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481187/ https://www.ncbi.nlm.nih.gov/pubmed/32908127 http://dx.doi.org/10.1038/s41467-020-18261-7 |