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Decorin expression is associated with predictive diffusion MR phenotypes of anti-VEGF efficacy in glioblastoma

Previous data suggest that apparent diffusion coefficient (ADC) imaging phenotypes predict survival response to anti-VEGF monotherapy in glioblastoma. However, the mechanism by which imaging may predict clinical response is unknown. We hypothesize that decorin (DCN), a proteoglycan implicated in the...

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Detalles Bibliográficos
Autores principales:	Patel, Kunal S., Yao, Jingwen, Raymond, Catalina, Yong, William, Everson, Richard, Liau, Linda M., Nathanson, David, Kornblum, Harley, Wang, Chencai, Oughourlian, Talia, Lai, Albert, Nghiemphu, Phioanh L., Pope, Whitney B., Cloughesy, Timothy F., Ellingson, Benjamin M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481206/ https://www.ncbi.nlm.nih.gov/pubmed/32908231 http://dx.doi.org/10.1038/s41598-020-71799-w

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