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Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion
The androgen receptor (AR) is the master regulator of prostate cancer (PCa) development, and inhibition of AR signalling is the most effective PCa treatment. AR is expressed in PCa cells and also in the PCa-associated stroma, including infiltrating macrophages. Macrophages have a decisive function i...
Autores principales: | Cioni, Bianca, Zaalberg, Anniek, van Beijnum, Judy R., Melis, Monique H. M., van Burgsteden, Johan, Muraro, Mauro J., Hooijberg, Erik, Peters, Dennis, Hofland, Ingrid, Lubeck, Yoni, de Jong, Jeroen, Sanders, Joyce, Vivié, Judith, van der Poel, Henk G., de Boer, Jan Paul, Griffioen, Arjan W., Zwart, Wilbert, Bergman, Andries M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481219/ https://www.ncbi.nlm.nih.gov/pubmed/32908142 http://dx.doi.org/10.1038/s41467-020-18313-y |
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