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Geriatric Interdisciplinary Home Rehabilitation After Hip Fracture in People with Dementia – A Subgroup Analysis of a Randomized Controlled Trial

PURPOSE: To investigate if the effects of geriatric interdisciplinary home rehabilitation after hip fracture were different among people with dementia compared to those without dementia and to describe the overall outcome after hip fracture in people with dementia. PATIENTS AND METHODS: A post hoc s...

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Autores principales: Karlsson, Åsa, Berggren, Monica, Olofsson, Birgitta, Stenvall, Michael, Gustafson, Yngve, Nordström, Peter, Lindelöf, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481284/
https://www.ncbi.nlm.nih.gov/pubmed/32943858
http://dx.doi.org/10.2147/CIA.S250809
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author Karlsson, Åsa
Berggren, Monica
Olofsson, Birgitta
Stenvall, Michael
Gustafson, Yngve
Nordström, Peter
Lindelöf, Nina
author_facet Karlsson, Åsa
Berggren, Monica
Olofsson, Birgitta
Stenvall, Michael
Gustafson, Yngve
Nordström, Peter
Lindelöf, Nina
author_sort Karlsson, Åsa
collection PubMed
description PURPOSE: To investigate if the effects of geriatric interdisciplinary home rehabilitation after hip fracture were different among people with dementia compared to those without dementia and to describe the overall outcome after hip fracture in people with dementia. PATIENTS AND METHODS: A post hoc subgroup analysis of a randomized controlled trial was conducted including 205 people with hip fracture, aged ≥70, living in ordinary housing or residential care facilities. Early discharge followed by individually designed interdisciplinary home rehabilitation for a maximum of 10 weeks was compared to in-hospital geriatric care according to a multifactorial rehabilitation program. Outcomes were hospital length of stay (LOS), readmissions, falls, mortality, performance in activities of daily living (ADL), and walking ability. RESULTS: Interdisciplinary home rehabilitation vs in-hospital care had comparable effects on falls and mortality between discharge and 12 months and on ADL and walking ability at 3 and 12 months regardless of whether the participants had dementia or not (P≥0.05 for all). Among participants with dementia, postoperative LOS was a median of 18 days (interquartile range [IQR] 14–30) in the home rehabilitation group vs 23 days (IQR 15–30) in the control group (P=0.254) with comparable numbers of readmissions after discharge. Dementia was associated with increased risk of falling (odds ratio [OR] 3.86; 95% confidence interval [CI]: 2.05–7.27; P<0.001) and increased mortality (OR 4.20; 95% CI 1.79–9.92, P=0.001) between discharge and 12 months and with greater dependence in ADL and walking at 3 and 12 months compared to participants without dementia (P<0.001 for all). CONCLUSION: The effects of geriatric interdisciplinary home rehabilitation vs in-hospital geriatric care did not differ in participants with and without dementia. However, the statistical power of this subgroup analysis was likely insufficient to detect differences between the groups. Dementia was associated with a substantial negative impact on the outcomes following the hip fracture. Our findings support offering interdisciplinary home rehabilitation after hip fracture to people with dementia.
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spelling pubmed-74812842020-09-16 Geriatric Interdisciplinary Home Rehabilitation After Hip Fracture in People with Dementia – A Subgroup Analysis of a Randomized Controlled Trial Karlsson, Åsa Berggren, Monica Olofsson, Birgitta Stenvall, Michael Gustafson, Yngve Nordström, Peter Lindelöf, Nina Clin Interv Aging Original Research PURPOSE: To investigate if the effects of geriatric interdisciplinary home rehabilitation after hip fracture were different among people with dementia compared to those without dementia and to describe the overall outcome after hip fracture in people with dementia. PATIENTS AND METHODS: A post hoc subgroup analysis of a randomized controlled trial was conducted including 205 people with hip fracture, aged ≥70, living in ordinary housing or residential care facilities. Early discharge followed by individually designed interdisciplinary home rehabilitation for a maximum of 10 weeks was compared to in-hospital geriatric care according to a multifactorial rehabilitation program. Outcomes were hospital length of stay (LOS), readmissions, falls, mortality, performance in activities of daily living (ADL), and walking ability. RESULTS: Interdisciplinary home rehabilitation vs in-hospital care had comparable effects on falls and mortality between discharge and 12 months and on ADL and walking ability at 3 and 12 months regardless of whether the participants had dementia or not (P≥0.05 for all). Among participants with dementia, postoperative LOS was a median of 18 days (interquartile range [IQR] 14–30) in the home rehabilitation group vs 23 days (IQR 15–30) in the control group (P=0.254) with comparable numbers of readmissions after discharge. Dementia was associated with increased risk of falling (odds ratio [OR] 3.86; 95% confidence interval [CI]: 2.05–7.27; P<0.001) and increased mortality (OR 4.20; 95% CI 1.79–9.92, P=0.001) between discharge and 12 months and with greater dependence in ADL and walking at 3 and 12 months compared to participants without dementia (P<0.001 for all). CONCLUSION: The effects of geriatric interdisciplinary home rehabilitation vs in-hospital geriatric care did not differ in participants with and without dementia. However, the statistical power of this subgroup analysis was likely insufficient to detect differences between the groups. Dementia was associated with a substantial negative impact on the outcomes following the hip fracture. Our findings support offering interdisciplinary home rehabilitation after hip fracture to people with dementia. Dove 2020-09-04 /pmc/articles/PMC7481284/ /pubmed/32943858 http://dx.doi.org/10.2147/CIA.S250809 Text en © 2020 Karlsson et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Karlsson, Åsa
Berggren, Monica
Olofsson, Birgitta
Stenvall, Michael
Gustafson, Yngve
Nordström, Peter
Lindelöf, Nina
Geriatric Interdisciplinary Home Rehabilitation After Hip Fracture in People with Dementia – A Subgroup Analysis of a Randomized Controlled Trial
title Geriatric Interdisciplinary Home Rehabilitation After Hip Fracture in People with Dementia – A Subgroup Analysis of a Randomized Controlled Trial
title_full Geriatric Interdisciplinary Home Rehabilitation After Hip Fracture in People with Dementia – A Subgroup Analysis of a Randomized Controlled Trial
title_fullStr Geriatric Interdisciplinary Home Rehabilitation After Hip Fracture in People with Dementia – A Subgroup Analysis of a Randomized Controlled Trial
title_full_unstemmed Geriatric Interdisciplinary Home Rehabilitation After Hip Fracture in People with Dementia – A Subgroup Analysis of a Randomized Controlled Trial
title_short Geriatric Interdisciplinary Home Rehabilitation After Hip Fracture in People with Dementia – A Subgroup Analysis of a Randomized Controlled Trial
title_sort geriatric interdisciplinary home rehabilitation after hip fracture in people with dementia – a subgroup analysis of a randomized controlled trial
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481284/
https://www.ncbi.nlm.nih.gov/pubmed/32943858
http://dx.doi.org/10.2147/CIA.S250809
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