Bruton’s Tyrosine Kinase (BTK) Inhibitor RN486 Overcomes ABCB1-Mediated Multidrug Resistance in Cancer Cells

Overexpression of ATP-binding cassette subfamily B member 1 (ABCB1) remains one of the most vital factors leading to multidrug resistance (MDR). It is important to enhance the effect and bioavailability of chemotherapeutic drugs that are substrates of ABCB1 transporter in ABCB1-overexpression cancer...

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Detalles Bibliográficos
Autores principales: Dong, Xing-Duo, Zhang, Meng, Ma, Xiubin, Wang, Jing-Quan, Lei, Zi-Ning, Teng, Qiu-Xu, Li, Yi-Dong, Lin, Lusheng, Feng, Weiguo, Chen, Zhe-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481333/
https://www.ncbi.nlm.nih.gov/pubmed/32984343
http://dx.doi.org/10.3389/fcell.2020.00865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481333/
https://www.ncbi.nlm.nih.gov/pubmed/32984343
http://dx.doi.org/10.3389/fcell.2020.00865

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