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AMPKα2 Overexpression Reduces Cardiomyocyte Ischemia-Reperfusion Injury Through Normalization of Mitochondrial Dynamics

Cardiac ischemia-reperfusion (I/R) injury is associated with mitochondrial dysfunction. Recent studies have reported that mitochondrial function is determined by mitochondrial dynamics. Here, we hypothesized that AMPKα2 functions as an upstream mediator that sustains mitochondrial dynamics in cardia...

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Detalles Bibliográficos
Autores principales: Deng, Yuanyan, Chen, Sainan, Zhang, Mingming, Li, Chen, He, Jing, Tan, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481335/
https://www.ncbi.nlm.nih.gov/pubmed/32984328
http://dx.doi.org/10.3389/fcell.2020.00833

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