Inhibition of Pendrin by a small molecule reduces Lipopolysaccharide-induced acute Lung Injury

Rationale: Pendrin is encoded by SLC26A4 and its mutation leads to congenital hearing loss. Additionally, pendrin is up-regulated in inflammatory airway diseases such as chronic obstructive pulmonary disease, allergic rhinitis, and asthma. In this study, the effects of a novel pendrin inhibitor, YS-...

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Detalles Bibliográficos
Autores principales: Lee, Eun Hye, Shin, Mi Hwa, Gi, Mia, Park, Jinhong, Song, Doona, Hyun, Young-Min, Ryu, Ji-Hwan, Seong, Je Kyung, Jeon, Yoon, Han, Gyoonhee, Namkung, Wan, Park, Moo Suk, Choi, Jae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481407/
https://www.ncbi.nlm.nih.gov/pubmed/32929324
http://dx.doi.org/10.7150/thno.46417

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