The peptide PROTAC modality: a novel strategy for targeted protein ubiquitination

Despite dramatic advances in drug discovery over the decades, effective therapeutic strategies for cancers treatment are still in urgent demands. PROteolysis TArgeting Chimera (PROTAC), a novel therapeutic modality, has been vigorously promoted in preclinical and clinical applications. Unlike small...

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Detalles Bibliográficos
Autores principales: Jin, Jinmei, Wu, Ye, Chen, Jinjiao, Shen, Yiwen, Zhang, Lijun, Zhang, Hong, Chen, Lili, Yuan, Hebao, Chen, Hongzhuan, Zhang, Weidong, Luan, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481416/
https://www.ncbi.nlm.nih.gov/pubmed/32929339
http://dx.doi.org/10.7150/thno.46985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481416/
https://www.ncbi.nlm.nih.gov/pubmed/32929339
http://dx.doi.org/10.7150/thno.46985

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