Dysregulated Kras/YY1/ZNF322A/Shh transcriptional axis enhances neo-angiogenesis to promote lung cancer progression

Angiogenesis enhances cancer metastasis and progression, however, the roles of transcription regulation in angiogenesis are not fully defined. ZNF322A is an oncogenic zinc-finger transcription factor. Here, we demonstrate a new mechanism of Kras mutation-driven ZNF322A transcriptional activation and...

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Detalles Bibliográficos
Autores principales: Lin, Che-Chung, Kuo, I-Ying, Wu, Li-Ting, Kuan, Wen-Hui, Liao, Sheng-You, Jen, Jayu, Yang, You-En, Tang, Cheng-Wei, Chen, Yi-Rong, Wang, Yi-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481419/
https://www.ncbi.nlm.nih.gov/pubmed/32929330
http://dx.doi.org/10.7150/thno.47491

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