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Y-Stent Rescue Technique for Failed Thrombectomy in Patients With Large Vessel Occlusion: A Case Series and Pooled Analysis

Objective: Y-stent thrombectomy is a recent rescue technique for failed thrombectomy in patients with emergent large vessel occlusion. We presented case series of using Y-stent rescue technique at different sites and investigate its feasibility and safety through pooled analysis of collected case re...

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Autores principales: Li, Zifu, Liu, Peng, Zhang, Lei, Zhang, Yongwei, Fang, Yibin, Xing, Pengfei, Huang, Qinghai, Yang, Pengfei, Liu, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481477/
https://www.ncbi.nlm.nih.gov/pubmed/32973671
http://dx.doi.org/10.3389/fneur.2020.00924
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author Li, Zifu
Liu, Peng
Zhang, Lei
Zhang, Yongwei
Fang, Yibin
Xing, Pengfei
Huang, Qinghai
Yang, Pengfei
Liu, Jianmin
author_facet Li, Zifu
Liu, Peng
Zhang, Lei
Zhang, Yongwei
Fang, Yibin
Xing, Pengfei
Huang, Qinghai
Yang, Pengfei
Liu, Jianmin
author_sort Li, Zifu
collection PubMed
description Objective: Y-stent thrombectomy is a recent rescue technique for failed thrombectomy in patients with emergent large vessel occlusion. We presented case series of using Y-stent rescue technique at different sites and investigate its feasibility and safety through pooled analysis of collected case report or series. Methods: Twenty-eight cases were screened from stroke databank who underwent thrombectomy between January 2015 and June 2019. Clinical, procedural, and follow-up data were investigated and pooled analysis of published literature was analyzed. Results: The occlusion sites include carotid terminus in 14 patients; siphon segment in 3; middle cerebral artery (MCA) in 4; basilar terminus in 7. The overall recanalization rate reached 85.7% (arterial occlusive lesion score 2–3); and final reperfusion rate 85.7% (modified Thrombolysis in Cerebral Infarction 2b−3). After literature review, totally, 52 cases were included. Good clinical outcome was achieved in 26 (50%) and mortality in 7 (17.3%). There is no significant difference on the SAH complication at different sites. Literature review shows no difference between each site in the reperfusion and complication rate. Conclusion: Our case series results suggest that high recanalization rate can be effectively achieved with Y-stent rescue technique for patients with refractory emergent large vessel occlusion. The safety of using this technique at different sites needs further investigation for patients.
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spelling pubmed-74814772020-09-23 Y-Stent Rescue Technique for Failed Thrombectomy in Patients With Large Vessel Occlusion: A Case Series and Pooled Analysis Li, Zifu Liu, Peng Zhang, Lei Zhang, Yongwei Fang, Yibin Xing, Pengfei Huang, Qinghai Yang, Pengfei Liu, Jianmin Front Neurol Neurology Objective: Y-stent thrombectomy is a recent rescue technique for failed thrombectomy in patients with emergent large vessel occlusion. We presented case series of using Y-stent rescue technique at different sites and investigate its feasibility and safety through pooled analysis of collected case report or series. Methods: Twenty-eight cases were screened from stroke databank who underwent thrombectomy between January 2015 and June 2019. Clinical, procedural, and follow-up data were investigated and pooled analysis of published literature was analyzed. Results: The occlusion sites include carotid terminus in 14 patients; siphon segment in 3; middle cerebral artery (MCA) in 4; basilar terminus in 7. The overall recanalization rate reached 85.7% (arterial occlusive lesion score 2–3); and final reperfusion rate 85.7% (modified Thrombolysis in Cerebral Infarction 2b−3). After literature review, totally, 52 cases were included. Good clinical outcome was achieved in 26 (50%) and mortality in 7 (17.3%). There is no significant difference on the SAH complication at different sites. Literature review shows no difference between each site in the reperfusion and complication rate. Conclusion: Our case series results suggest that high recanalization rate can be effectively achieved with Y-stent rescue technique for patients with refractory emergent large vessel occlusion. The safety of using this technique at different sites needs further investigation for patients. Frontiers Media S.A. 2020-08-27 /pmc/articles/PMC7481477/ /pubmed/32973671 http://dx.doi.org/10.3389/fneur.2020.00924 Text en Copyright © 2020 Li, Liu, Zhang, Zhang, Fang, Xing, Huang, Yang and Liu. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Li, Zifu
Liu, Peng
Zhang, Lei
Zhang, Yongwei
Fang, Yibin
Xing, Pengfei
Huang, Qinghai
Yang, Pengfei
Liu, Jianmin
Y-Stent Rescue Technique for Failed Thrombectomy in Patients With Large Vessel Occlusion: A Case Series and Pooled Analysis
title Y-Stent Rescue Technique for Failed Thrombectomy in Patients With Large Vessel Occlusion: A Case Series and Pooled Analysis
title_full Y-Stent Rescue Technique for Failed Thrombectomy in Patients With Large Vessel Occlusion: A Case Series and Pooled Analysis
title_fullStr Y-Stent Rescue Technique for Failed Thrombectomy in Patients With Large Vessel Occlusion: A Case Series and Pooled Analysis
title_full_unstemmed Y-Stent Rescue Technique for Failed Thrombectomy in Patients With Large Vessel Occlusion: A Case Series and Pooled Analysis
title_short Y-Stent Rescue Technique for Failed Thrombectomy in Patients With Large Vessel Occlusion: A Case Series and Pooled Analysis
title_sort y-stent rescue technique for failed thrombectomy in patients with large vessel occlusion: a case series and pooled analysis
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481477/
https://www.ncbi.nlm.nih.gov/pubmed/32973671
http://dx.doi.org/10.3389/fneur.2020.00924
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