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EGFR circulating tumour DNA testing: identification of predictors of ctDNA detection and implications for survival outcomes
BACKGROUND: EGFR T790M testing is the standard of care for activating EGFR mutation (EGFRm) non-small cell lung cancer (NSCLC) progressing on 1st/2nd generation TKIs to select patients for osimertinib. Despite sensitive assays, detection of circulating tumour deoxyribonucleic acid (ctDNA) is variabl...
Autores principales: | Pender, Alexandra, Hughesman, Curtis, Law, Elaine, Kristanti, Amadea, McNeil, Kelly, Wong, Selina, Tucker, Tracy, Bosdet, Ian, Young, Sean, Laskin, Janessa, Karsan, Aly, Yip, Stephen, Ho, Cheryl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481591/ https://www.ncbi.nlm.nih.gov/pubmed/32953487 http://dx.doi.org/10.21037/tlcr-19-581 |
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