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Drug reaction with eosinophilia and systemic symptoms (DRESS) with severe and atypical lung involvement
Drug reaction with eosinophilia and systemic symptoms is a rare and potentially fatal drug hypersensitivity reaction. Reactions include skin eruption, fever, hematologic abnormalities (eosinophilia or atypical lymphocytosis), enlarged lymph nodes, and/or organic involvement. The liver is the most co...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481882/ https://www.ncbi.nlm.nih.gov/pubmed/32944113 http://dx.doi.org/10.1016/j.radcr.2020.08.037 |
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author | Guerrero Gómez, Diego Armando París Zorro, Sara Aponte Barrios, Wilmer Carrillo Bayona, Jorge Alberto |
author_facet | Guerrero Gómez, Diego Armando París Zorro, Sara Aponte Barrios, Wilmer Carrillo Bayona, Jorge Alberto |
author_sort | Guerrero Gómez, Diego Armando |
collection | PubMed |
description | Drug reaction with eosinophilia and systemic symptoms is a rare and potentially fatal drug hypersensitivity reaction. Reactions include skin eruption, fever, hematologic abnormalities (eosinophilia or atypical lymphocytosis), enlarged lymph nodes, and/or organic involvement. The liver is the most commonly compromised organ. We present a case of drug reaction with eosinophilia and systemic symptoms associated with Naproxen intake in a young female patient with severe lung involvement. The patient's chest tomography highlights the presence of adenomegalies, pericardial and pleural effusion, peribroncovascular consolidations, and centrilobular nodules. After reviewing the literature few similar cases were found. The main radiological alterations in those cases included interstitial opacities attributed to pneumonitis. Therefore, this case study is considered an unusual case with atypical presentation of drug-induced eosinophilic lung disease. |
format | Online Article Text |
id | pubmed-7481882 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-74818822020-09-16 Drug reaction with eosinophilia and systemic symptoms (DRESS) with severe and atypical lung involvement Guerrero Gómez, Diego Armando París Zorro, Sara Aponte Barrios, Wilmer Carrillo Bayona, Jorge Alberto Radiol Case Rep Case Report Drug reaction with eosinophilia and systemic symptoms is a rare and potentially fatal drug hypersensitivity reaction. Reactions include skin eruption, fever, hematologic abnormalities (eosinophilia or atypical lymphocytosis), enlarged lymph nodes, and/or organic involvement. The liver is the most commonly compromised organ. We present a case of drug reaction with eosinophilia and systemic symptoms associated with Naproxen intake in a young female patient with severe lung involvement. The patient's chest tomography highlights the presence of adenomegalies, pericardial and pleural effusion, peribroncovascular consolidations, and centrilobular nodules. After reviewing the literature few similar cases were found. The main radiological alterations in those cases included interstitial opacities attributed to pneumonitis. Therefore, this case study is considered an unusual case with atypical presentation of drug-induced eosinophilic lung disease. Elsevier 2020-09-04 /pmc/articles/PMC7481882/ /pubmed/32944113 http://dx.doi.org/10.1016/j.radcr.2020.08.037 Text en © 2020 The Authors. Published by Elsevier Inc. on behalf of University of Washington. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Guerrero Gómez, Diego Armando París Zorro, Sara Aponte Barrios, Wilmer Carrillo Bayona, Jorge Alberto Drug reaction with eosinophilia and systemic symptoms (DRESS) with severe and atypical lung involvement |
title | Drug reaction with eosinophilia and systemic symptoms (DRESS) with severe and atypical lung involvement |
title_full | Drug reaction with eosinophilia and systemic symptoms (DRESS) with severe and atypical lung involvement |
title_fullStr | Drug reaction with eosinophilia and systemic symptoms (DRESS) with severe and atypical lung involvement |
title_full_unstemmed | Drug reaction with eosinophilia and systemic symptoms (DRESS) with severe and atypical lung involvement |
title_short | Drug reaction with eosinophilia and systemic symptoms (DRESS) with severe and atypical lung involvement |
title_sort | drug reaction with eosinophilia and systemic symptoms (dress) with severe and atypical lung involvement |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481882/ https://www.ncbi.nlm.nih.gov/pubmed/32944113 http://dx.doi.org/10.1016/j.radcr.2020.08.037 |
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