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Induced Pluripotent Stem Cell Meets Severe Combined Immunodeficiency

Severe combined immunodeficiency (SCID) is classified as a primary immunodeficiency, which is characterized by impaired T-lymphocytes differentiation. IL2RG, IL7Ralpha, JAK3, ADA, RAG1/RAG2, and DCLE1C (Artemis) are the most defective genes in SCID. The most recent SCID therapies are based on gene t...

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Detalles Bibliográficos
Autores principales:	Kouchaki, Reza, Abd-Nikfarjam, Bahareh, Maali, Amirhosein, Abroun, Saeid, Foroughi, Farshad, Ghaffari, Sasan, Azad, Mehdi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royan Institute 2020
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481889/ https://www.ncbi.nlm.nih.gov/pubmed/32779449 http://dx.doi.org/10.22074/cellj.2020.6849

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