Metformin Attenuates Brain Injury by Inhibiting Inflammation and Regulating Tight Junction Proteins in Septic Rats

OBJECTIVE: Metformin has a potent inhibitory activity against inflammation and oxidative stress, which inevitably occur in sepsis-associated encephalopathy (SAE). The precise mechanisms underlying neuroprotective effects of metformin in SAE, are still unclear. In the present work, the protective eff...

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Detalles Bibliográficos
Autores principales: Ismail Hassan, Fatima, Didari, Tina, Baeeri, Maryam, Gholami, Mahdi, Haghi-Aminjan, Hamed, Khalid, Madiha, Navaei-Nigjeh, Mona, Rahimifard, Mahban, Solgi, Sara, Abdollahi, Mohammad, Mojtahedzadeh, Mojtaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481907/
https://www.ncbi.nlm.nih.gov/pubmed/32779431
http://dx.doi.org/10.22074/cellj.2020.7046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481907/
https://www.ncbi.nlm.nih.gov/pubmed/32779431
http://dx.doi.org/10.22074/cellj.2020.7046

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