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Peripheral Circulation and Astrocytes Contribute to the MSC-Mediated Increase in IGF-1 Levels in the Infarct Cortex in a dMCAO Rat Model

MATERIALS AND METHODS: Ischemic brain injury was induced by dMCAO in Sprague-Dawley rats. The transplantation group received MSC infusion 1 h after dMCAO. Expression of IGF-1 in GFAP+ astrocytes, Iba-1+ microglia/macrophages, CD3+ lymphocytes, Ly6C+ monocytes/macrophages, and neutrophil elastase (NE...

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Detalles Bibliográficos
Autores principales:	Li, Xiaobo, Yu, Wenxiu, Guan, Yunqian, Zou, Haiqiang, Liang, Zhaohui, Huang, Min, Zhao, Renchao, Zhao, Chunsong, Ren, Zhenhua, Chen, Zhiguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481998/ https://www.ncbi.nlm.nih.gov/pubmed/32952570 http://dx.doi.org/10.1155/2020/8853444

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