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Construction and Preclinical Evaluation of (211)At Labeled Anti-mesothelin Antibodies as Potential Targeted Alpha Therapy Drugs
Targeted alpha therapy (TAT) is a promising tumor therapy that can specifically transport α particle to the vicinity of tumor cells while the normal cells are only slightly irradiated. Mesothelin is a highly promising molecular signature for many types of solid tumors including malignant mesotheliom...
Autores principales: | Wang, Xudong, Ma, Wenzong, Liu, Weihao, Ma, Huan, Yang, Yuanyou, Wang, Yugang, Liu, Ning, Yang, Gen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482154/ https://www.ncbi.nlm.nih.gov/pubmed/32648573 http://dx.doi.org/10.1093/jrr/rraa049 |
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