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The Polygenic and Monogenic Basis of Blood Traits and Diseases

Blood cells play essential roles in human health, underpinning physiological processes such as immunity, oxygen transport, and clotting, which when perturbed cause a significant global health burden. Here we integrate data from UK Biobank and a large-scale international collaborative effort, includi...

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Detalles Bibliográficos
Autores principales: Vuckovic, Dragana, Bao, Erik L., Akbari, Parsa, Lareau, Caleb A., Mousas, Abdou, Jiang, Tao, Chen, Ming-Huei, Raffield, Laura M., Tardaguila, Manuel, Huffman, Jennifer E., Ritchie, Scott C., Megy, Karyn, Ponstingl, Hannes, Penkett, Christopher J., Albers, Patrick K., Wigdor, Emilie M., Sakaue, Saori, Moscati, Arden, Manansala, Regina, Lo, Ken Sin, Qian, Huijun, Akiyama, Masato, Bartz, Traci M., Ben-Shlomo, Yoav, Beswick, Andrew, Bork-Jensen, Jette, Bottinger, Erwin P., Brody, Jennifer A., van Rooij, Frank J.A., Chitrala, Kumaraswamy N., Wilson, Peter W.F., Choquet, Hélène, Danesh, John, Di Angelantonio, Emanuele, Dimou, Niki, Ding, Jingzhong, Elliott, Paul, Esko, Tõnu, Evans, Michele K., Felix, Stephan B., Floyd, James S., Broer, Linda, Grarup, Niels, Guo, Michael H., Guo, Qi, Greinacher, Andreas, Haessler, Jeff, Hansen, Torben, Howson, Joanna M.M., Huang, Wei, Jorgenson, Eric, Kacprowski, Tim, Kähönen, Mika, Kamatani, Yoichiro, Kanai, Masahiro, Karthikeyan, Savita, Koskeridis, Fotios, Lange, Leslie A., Lehtimäki, Terho, Linneberg, Allan, Liu, Yongmei, Lyytikäinen, Leo-Pekka, Manichaikul, Ani, Matsuda, Koichi, Mohlke, Karen L., Mononen, Nina, Murakami, Yoshinori, Nadkarni, Girish N., Nikus, Kjell, Pankratz, Nathan, Pedersen, Oluf, Preuss, Michael, Psaty, Bruce M., Raitakari, Olli T., Rich, Stephen S., Rodriguez, Benjamin A.T., Rosen, Jonathan D., Rotter, Jerome I., Schubert, Petra, Spracklen, Cassandra N., Surendran, Praveen, Tang, Hua, Tardif, Jean-Claude, Ghanbari, Mohsen, Völker, Uwe, Völzke, Henry, Watkins, Nicholas A., Weiss, Stefan, Cai, Na, Kundu, Kousik, Watt, Stephen B., Walter, Klaudia, Zonderman, Alan B., Cho, Kelly, Li, Yun, Loos, Ruth J.F., Knight, Julian C., Georges, Michel, Stegle, Oliver, Evangelou, Evangelos, Okada, Yukinori, Roberts, David J., Inouye, Michael, Johnson, Andrew D., Auer, Paul L., Astle, William J., Reiner, Alexander P., Butterworth, Adam S., Ouwehand, Willem H., Lettre, Guillaume, Sankaran, Vijay G., Soranzo, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482360/
https://www.ncbi.nlm.nih.gov/pubmed/32888494
http://dx.doi.org/10.1016/j.cell.2020.08.008

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