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Decoding the mechanisms underlying cell-fate decision-making during stem cell differentiation by random circuit perturbation
Stem cells can precisely and robustly undergo cellular differentiation and lineage commitment, referred to as stemness. However, how the gene network underlying stemness regulation reliably specifies cell fates is not well understood. To address this question, we applied a recently developed computa...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482558/ https://www.ncbi.nlm.nih.gov/pubmed/32781932 http://dx.doi.org/10.1098/rsif.2020.0500 |