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Quantum Dot-Conjugated SARS-CoV-2 Spike Pseudo-Virions Enable Tracking of Angiotensin Converting Enzyme 2 Binding and Endocytosis

[Image: see text] The first step of SARS-CoV-2 infection is binding of the spike protein’s receptor binding domain to the host cell’s ACE2 receptor on the plasma membrane. Here, we have generated a versatile imaging probe using recombinant Spike receptor binding domain conjugated to fluorescent quan...

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Detalles Bibliográficos
Autores principales:	Gorshkov, Kirill, Susumu, Kimihiro, Chen, Jiji, Xu, Miao, Pradhan, Manisha, Zhu, Wei, Hu, Xin, Breger, Joyce C., Wolak, Mason, Oh, Eunkeu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482579/ https://www.ncbi.nlm.nih.gov/pubmed/32845122 http://dx.doi.org/10.1021/acsnano.0c05975

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