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EREG-driven oncogenesis of Head and Neck Squamous Cell Carcinoma exhibits higher sensitivity to Erlotinib therapy

Rationale: The oncogenesis of head and neck squamous cell carcinoma (HNSCC) is believed to result from oncogene activation and tumor suppressor inactivation. Here, we identified a new oncogenic role for the EREG gene in HNSCC. Methods: The TCGA database and immunohistochemistry assay were used to an...

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Detalles Bibliográficos
Autores principales: Liu, Shuli, Wang, Yang, Han, Yong, Xia, Weiya, Zhang, Ling, Xu, Shengming, Ju, Houyu, Zhang, Xiangkai, Ren, Guoxin, Liu, Liu, Ye, Weimin, Zhang, Zhiyuan, Hu, Jingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482801/
https://www.ncbi.nlm.nih.gov/pubmed/32929368
http://dx.doi.org/10.7150/thno.47176

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