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The ERα-miR-575-p27 feedback loop regulates tamoxifen sensitivity in ER-positive Breast Cancer

Background: Breast cancer is the most common malignancy, and approximately 70% of breast cancers are estrogen receptor-α (ERα) positive. The anti-estrogen tamoxifen is a highly effective and commonly used treatment for patients with ER+ breast cancer. However, 30% of breast cancer patients fail adju...

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Detalles Bibliográficos
Autores principales: Liu, Shu-Shu, Li, Yun, Zhang, Hui, Zhang, Di, Zhang, Xiao-Bei, Wang, Xin, Yu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482812/
https://www.ncbi.nlm.nih.gov/pubmed/32929377
http://dx.doi.org/10.7150/thno.46297