E. coli nitroreductase NfsA is a reporter gene for non-invasive PET imaging in cancer gene therapy applications

The use of reporter genes to non-invasively image molecular processes inside cells has significant translational potential, particularly in the context of systemically administered gene therapy vectors and adoptively administered cells such as immune or stem cell based therapies. Bacterial nitroredu...

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Detalles Bibliográficos
Autores principales: Mowday, Alexandra Marie, Copp, Janine Naomi, Syddall, Sophie Philippa, Dubois, Ludwig Jerome, Wang, Jingli, Lieuwes, Natasja Gabi, Biemans, Rianne, Ashoorzadeh, Amir, Abbattista, Maria Rosaria, Williams, Elsie May, Guise, Christopher Paul, Lambin, Philippe, Ackerley, David Francis, Smaill, Jeff Bruce, Theys, Jan, Patterson, Adam Vorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482819/
https://www.ncbi.nlm.nih.gov/pubmed/32929365
http://dx.doi.org/10.7150/thno.46826

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