Cargando…

CDK4/6 inhibition promotes immune infiltration in ovarian cancer and synergizes with PD-1 blockade in a B cell-dependent manner

Great progress has been made in the field of tumor immunotherapy in the past decade. However, the therapeutic effects of immune checkpoint blockade (ICB) against ovarian cancer are still limited. Recently, an inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6i) has been reported to enhance antitu...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Qian-Feng, Li, Jia, Jiang, Kuo, Wang, Rui, Ge, Jun-li, Yang, Hong, Liu, Shu-Juan, Jia, Lin-Tao, Wang, Lei, Chen, Bi-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482823/
https://www.ncbi.nlm.nih.gov/pubmed/32929370
http://dx.doi.org/10.7150/thno.44871