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Polyploidy of semi-cloned embryos generated from parthenogenetic haploid embryonic stem cells

In mammals, the fusion of two gametes, an oocyte and a spermatozoon, during fertilization forms a totipotent zygote. There has been no reported case of adult mammal development by natural parthenogenesis, in which embryos develop from unfertilized oocytes. The genome and epigenetic information of ha...

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Detalles Bibliográficos
Autores principales: Aizawa, Eishi, Dumeau, Charles-Etienne, Freimann, Remo, Di Minin, Giulio, Wutz, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482839/
https://www.ncbi.nlm.nih.gov/pubmed/32911495
http://dx.doi.org/10.1371/journal.pone.0233072