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The metronomic combination of paclitaxel with cholinergic agonists inhibits triple negative breast tumor progression. Participation of M(2) receptor subtype
Triple negative tumors are more aggressive than other breast cancer subtypes and there is a lack of specific therapeutic targets on them. Since muscarinic receptors have been linked to tumor progression, we investigated the effect of metronomic therapy employing a traditional anti-cancer drug, pacli...
Autores principales: | Español, Alejandro J., Salem, Agustina, Di Bari, María, Cristofaro, Ilaria, Sanchez, Yamila, Tata, Ada M., Sales, María E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482849/ https://www.ncbi.nlm.nih.gov/pubmed/32911509 http://dx.doi.org/10.1371/journal.pone.0226450 |
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