A role for gorilla APOBEC3G in shaping lentivirus evolution including transmission to humans

The APOBEC3 deaminases are potent inhibitors of virus replication and barriers to cross-species transmission. For simian immunodeficiency virus (SIV) to transmit to a new primate host, as happened multiple times to seed the ongoing HIV-1 epidemic, the viral infectivity factor (Vif) must be capable o...

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Detalles Bibliográficos
Autores principales: Nakano, Yusuke, Yamamoto, Keisuke, Ueda, Mahoko Takahashi, Soper, Andrew, Konno, Yoriyuki, Kimura, Izumi, Uriu, Keiya, Kumata, Ryuichi, Aso, Hirofumi, Misawa, Naoko, Nagaoka, Shumpei, Shimizu, Soma, Mitsumune, Keito, Kosugi, Yusuke, Juarez-Fernandez, Guillermo, Ito, Jumpei, Nakagawa, So, Ikeda, Terumasa, Koyanagi, Yoshio, Harris, Reuben S., Sato, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482973/
https://www.ncbi.nlm.nih.gov/pubmed/32913367
http://dx.doi.org/10.1371/journal.ppat.1008812

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