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Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry)

BACKGROUND: According to the medical literature, both on-pump and off-pump coronary artery surgery is safe and effective in octogenarians. OBJECTIVES: The aim of our study was to examine the epidemiology, in-hospital outcomes and long-term follow-up results in octogenarians undergoing off-pump and o...

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Autores principales: Knapik, Piotr, Hirnle, Grzegorz, Kowalczuk-Wieteska, Anetta, O.Zembala, Michał, Pawlak, Szymon, Hrapkowicz, Tomasz, Przybyłowski, Piotr, Nadziakiewicz, Paweł, Cieśla, Daniel, Perek, Bartłomiej, Kapelak, Bogusław, Cisowski, Marek, Rogowski, Jan, Pietrzyk, Edward, Tobota, Zdzisław, Zembala, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482977/
https://www.ncbi.nlm.nih.gov/pubmed/32913359
http://dx.doi.org/10.1371/journal.pone.0238880
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author Knapik, Piotr
Hirnle, Grzegorz
Kowalczuk-Wieteska, Anetta
O.Zembala, Michał
Pawlak, Szymon
Hrapkowicz, Tomasz
Przybyłowski, Piotr
Nadziakiewicz, Paweł
Cieśla, Daniel
Perek, Bartłomiej
Kapelak, Bogusław
Cisowski, Marek
Rogowski, Jan
Pietrzyk, Edward
Tobota, Zdzisław
Zembala, Marian
author_facet Knapik, Piotr
Hirnle, Grzegorz
Kowalczuk-Wieteska, Anetta
O.Zembala, Michał
Pawlak, Szymon
Hrapkowicz, Tomasz
Przybyłowski, Piotr
Nadziakiewicz, Paweł
Cieśla, Daniel
Perek, Bartłomiej
Kapelak, Bogusław
Cisowski, Marek
Rogowski, Jan
Pietrzyk, Edward
Tobota, Zdzisław
Zembala, Marian
author_sort Knapik, Piotr
collection PubMed
description BACKGROUND: According to the medical literature, both on-pump and off-pump coronary artery surgery is safe and effective in octogenarians. OBJECTIVES: The aim of our study was to examine the epidemiology, in-hospital outcomes and long-term follow-up results in octogenarians undergoing off-pump and on-pump coronary artery surgery utilizing nationwide registry data. METHODS: All octogenarians (≥ 80 years) enrolled in the Polish National Registry of Cardiac Surgical Procedures (KROK Registry), who underwent isolated coronary surgery between January 2006 and September 2017 were identified. Preoperative data, perioperative complications, hospital mortality and long-term mortality were analyzed. Unadjusted and propensity-matched comparisons were performed between octogenarians undergoing off-pump and on-pump coronary artery bypass surgery. RESULTS: Octogenarians accounted for 4.1% of the total population undergoing coronary artery surgery in Poland during the analyzed period (n = 152,631) and this percentage is increasing. Among 6,006 analyzed patients, 2,744 (45.7%) were operated on-pump and 3,262 (54.3%) were operated off-pump. Propensity-matched analysis revealed that patients operated on-pump were more often reoperated due to postoperative bleeding and their in-hospital mortality was higher (6.6% vs 4.5%, p = 0.006 and 8.7% vs 5.8%, p = 0.001, respectively). Long-term all-cause mortality was lower among patients operated off-pump (p = 0.013). CONCLUSION: On the basis of our findings we suggest that off pump technique should be considered as perfectly acceptable in octogenarians.
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spelling pubmed-74829772020-09-21 Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry) Knapik, Piotr Hirnle, Grzegorz Kowalczuk-Wieteska, Anetta O.Zembala, Michał Pawlak, Szymon Hrapkowicz, Tomasz Przybyłowski, Piotr Nadziakiewicz, Paweł Cieśla, Daniel Perek, Bartłomiej Kapelak, Bogusław Cisowski, Marek Rogowski, Jan Pietrzyk, Edward Tobota, Zdzisław Zembala, Marian PLoS One Research Article BACKGROUND: According to the medical literature, both on-pump and off-pump coronary artery surgery is safe and effective in octogenarians. OBJECTIVES: The aim of our study was to examine the epidemiology, in-hospital outcomes and long-term follow-up results in octogenarians undergoing off-pump and on-pump coronary artery surgery utilizing nationwide registry data. METHODS: All octogenarians (≥ 80 years) enrolled in the Polish National Registry of Cardiac Surgical Procedures (KROK Registry), who underwent isolated coronary surgery between January 2006 and September 2017 were identified. Preoperative data, perioperative complications, hospital mortality and long-term mortality were analyzed. Unadjusted and propensity-matched comparisons were performed between octogenarians undergoing off-pump and on-pump coronary artery bypass surgery. RESULTS: Octogenarians accounted for 4.1% of the total population undergoing coronary artery surgery in Poland during the analyzed period (n = 152,631) and this percentage is increasing. Among 6,006 analyzed patients, 2,744 (45.7%) were operated on-pump and 3,262 (54.3%) were operated off-pump. Propensity-matched analysis revealed that patients operated on-pump were more often reoperated due to postoperative bleeding and their in-hospital mortality was higher (6.6% vs 4.5%, p = 0.006 and 8.7% vs 5.8%, p = 0.001, respectively). Long-term all-cause mortality was lower among patients operated off-pump (p = 0.013). CONCLUSION: On the basis of our findings we suggest that off pump technique should be considered as perfectly acceptable in octogenarians. Public Library of Science 2020-09-10 /pmc/articles/PMC7482977/ /pubmed/32913359 http://dx.doi.org/10.1371/journal.pone.0238880 Text en © 2020 Knapik et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Knapik, Piotr
Hirnle, Grzegorz
Kowalczuk-Wieteska, Anetta
O.Zembala, Michał
Pawlak, Szymon
Hrapkowicz, Tomasz
Przybyłowski, Piotr
Nadziakiewicz, Paweł
Cieśla, Daniel
Perek, Bartłomiej
Kapelak, Bogusław
Cisowski, Marek
Rogowski, Jan
Pietrzyk, Edward
Tobota, Zdzisław
Zembala, Marian
Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry)
title Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry)
title_full Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry)
title_fullStr Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry)
title_full_unstemmed Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry)
title_short Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry)
title_sort off-pump versus on-pump coronary artery surgery in octogenarians (from the krok registry)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482977/
https://www.ncbi.nlm.nih.gov/pubmed/32913359
http://dx.doi.org/10.1371/journal.pone.0238880
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