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Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry)
BACKGROUND: According to the medical literature, both on-pump and off-pump coronary artery surgery is safe and effective in octogenarians. OBJECTIVES: The aim of our study was to examine the epidemiology, in-hospital outcomes and long-term follow-up results in octogenarians undergoing off-pump and o...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482977/ https://www.ncbi.nlm.nih.gov/pubmed/32913359 http://dx.doi.org/10.1371/journal.pone.0238880 |
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author | Knapik, Piotr Hirnle, Grzegorz Kowalczuk-Wieteska, Anetta O.Zembala, Michał Pawlak, Szymon Hrapkowicz, Tomasz Przybyłowski, Piotr Nadziakiewicz, Paweł Cieśla, Daniel Perek, Bartłomiej Kapelak, Bogusław Cisowski, Marek Rogowski, Jan Pietrzyk, Edward Tobota, Zdzisław Zembala, Marian |
author_facet | Knapik, Piotr Hirnle, Grzegorz Kowalczuk-Wieteska, Anetta O.Zembala, Michał Pawlak, Szymon Hrapkowicz, Tomasz Przybyłowski, Piotr Nadziakiewicz, Paweł Cieśla, Daniel Perek, Bartłomiej Kapelak, Bogusław Cisowski, Marek Rogowski, Jan Pietrzyk, Edward Tobota, Zdzisław Zembala, Marian |
author_sort | Knapik, Piotr |
collection | PubMed |
description | BACKGROUND: According to the medical literature, both on-pump and off-pump coronary artery surgery is safe and effective in octogenarians. OBJECTIVES: The aim of our study was to examine the epidemiology, in-hospital outcomes and long-term follow-up results in octogenarians undergoing off-pump and on-pump coronary artery surgery utilizing nationwide registry data. METHODS: All octogenarians (≥ 80 years) enrolled in the Polish National Registry of Cardiac Surgical Procedures (KROK Registry), who underwent isolated coronary surgery between January 2006 and September 2017 were identified. Preoperative data, perioperative complications, hospital mortality and long-term mortality were analyzed. Unadjusted and propensity-matched comparisons were performed between octogenarians undergoing off-pump and on-pump coronary artery bypass surgery. RESULTS: Octogenarians accounted for 4.1% of the total population undergoing coronary artery surgery in Poland during the analyzed period (n = 152,631) and this percentage is increasing. Among 6,006 analyzed patients, 2,744 (45.7%) were operated on-pump and 3,262 (54.3%) were operated off-pump. Propensity-matched analysis revealed that patients operated on-pump were more often reoperated due to postoperative bleeding and their in-hospital mortality was higher (6.6% vs 4.5%, p = 0.006 and 8.7% vs 5.8%, p = 0.001, respectively). Long-term all-cause mortality was lower among patients operated off-pump (p = 0.013). CONCLUSION: On the basis of our findings we suggest that off pump technique should be considered as perfectly acceptable in octogenarians. |
format | Online Article Text |
id | pubmed-7482977 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-74829772020-09-21 Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry) Knapik, Piotr Hirnle, Grzegorz Kowalczuk-Wieteska, Anetta O.Zembala, Michał Pawlak, Szymon Hrapkowicz, Tomasz Przybyłowski, Piotr Nadziakiewicz, Paweł Cieśla, Daniel Perek, Bartłomiej Kapelak, Bogusław Cisowski, Marek Rogowski, Jan Pietrzyk, Edward Tobota, Zdzisław Zembala, Marian PLoS One Research Article BACKGROUND: According to the medical literature, both on-pump and off-pump coronary artery surgery is safe and effective in octogenarians. OBJECTIVES: The aim of our study was to examine the epidemiology, in-hospital outcomes and long-term follow-up results in octogenarians undergoing off-pump and on-pump coronary artery surgery utilizing nationwide registry data. METHODS: All octogenarians (≥ 80 years) enrolled in the Polish National Registry of Cardiac Surgical Procedures (KROK Registry), who underwent isolated coronary surgery between January 2006 and September 2017 were identified. Preoperative data, perioperative complications, hospital mortality and long-term mortality were analyzed. Unadjusted and propensity-matched comparisons were performed between octogenarians undergoing off-pump and on-pump coronary artery bypass surgery. RESULTS: Octogenarians accounted for 4.1% of the total population undergoing coronary artery surgery in Poland during the analyzed period (n = 152,631) and this percentage is increasing. Among 6,006 analyzed patients, 2,744 (45.7%) were operated on-pump and 3,262 (54.3%) were operated off-pump. Propensity-matched analysis revealed that patients operated on-pump were more often reoperated due to postoperative bleeding and their in-hospital mortality was higher (6.6% vs 4.5%, p = 0.006 and 8.7% vs 5.8%, p = 0.001, respectively). Long-term all-cause mortality was lower among patients operated off-pump (p = 0.013). CONCLUSION: On the basis of our findings we suggest that off pump technique should be considered as perfectly acceptable in octogenarians. Public Library of Science 2020-09-10 /pmc/articles/PMC7482977/ /pubmed/32913359 http://dx.doi.org/10.1371/journal.pone.0238880 Text en © 2020 Knapik et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Knapik, Piotr Hirnle, Grzegorz Kowalczuk-Wieteska, Anetta O.Zembala, Michał Pawlak, Szymon Hrapkowicz, Tomasz Przybyłowski, Piotr Nadziakiewicz, Paweł Cieśla, Daniel Perek, Bartłomiej Kapelak, Bogusław Cisowski, Marek Rogowski, Jan Pietrzyk, Edward Tobota, Zdzisław Zembala, Marian Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry) |
title | Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry) |
title_full | Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry) |
title_fullStr | Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry) |
title_full_unstemmed | Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry) |
title_short | Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry) |
title_sort | off-pump versus on-pump coronary artery surgery in octogenarians (from the krok registry) |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482977/ https://www.ncbi.nlm.nih.gov/pubmed/32913359 http://dx.doi.org/10.1371/journal.pone.0238880 |
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