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Renal intravascular large B cell lymphoma: the first case report in Korea and a review of the literature
Herein, we describe the first case of renal intravascular large B cell lymphoma in Korea occurring in a 66-year-old female. She presented with mild fever and dyspnea. On physical and laboratory evaluations, hemophagocytic lymphohistiocytosis was suspected, but the bone marrow biopsy results were unr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Pathologists and the Korean Society for Cytopathology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483029/ https://www.ncbi.nlm.nih.gov/pubmed/32781826 http://dx.doi.org/10.4132/jptm.2020.06.18 |
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author | Kim, Moonsik Chung, Haerim Yang, Woo Ick Jeong, Hyeon Joo |
author_facet | Kim, Moonsik Chung, Haerim Yang, Woo Ick Jeong, Hyeon Joo |
author_sort | Kim, Moonsik |
collection | PubMed |
description | Herein, we describe the first case of renal intravascular large B cell lymphoma in Korea occurring in a 66-year-old female. She presented with mild fever and dyspnea. On physical and laboratory evaluations, hemophagocytic lymphohistiocytosis was suspected, but the bone marrow biopsy results were unremarkable. During the work-up, massive proteinuria developed, which led to a renal biopsy. The renal architecture was relatively well-preserved, but the glomeruli were hypercellular with the infiltration of atypical, large lymphoid cells with increased nucleus-cytoplasm ratio and clumped chromatin. Similar cells were also present in the peritubular capillaries. The tumor cells exhibited membranous staining for CD20 and CD79a. After the diagnosis of intravascular large B cell lymphoma, the patient received rituximab-based chemotherapy under close follow-up. |
format | Online Article Text |
id | pubmed-7483029 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Korean Society of Pathologists and the Korean Society for Cytopathology |
record_format | MEDLINE/PubMed |
spelling | pubmed-74830292020-09-21 Renal intravascular large B cell lymphoma: the first case report in Korea and a review of the literature Kim, Moonsik Chung, Haerim Yang, Woo Ick Jeong, Hyeon Joo J Pathol Transl Med Case Study Herein, we describe the first case of renal intravascular large B cell lymphoma in Korea occurring in a 66-year-old female. She presented with mild fever and dyspnea. On physical and laboratory evaluations, hemophagocytic lymphohistiocytosis was suspected, but the bone marrow biopsy results were unremarkable. During the work-up, massive proteinuria developed, which led to a renal biopsy. The renal architecture was relatively well-preserved, but the glomeruli were hypercellular with the infiltration of atypical, large lymphoid cells with increased nucleus-cytoplasm ratio and clumped chromatin. Similar cells were also present in the peritubular capillaries. The tumor cells exhibited membranous staining for CD20 and CD79a. After the diagnosis of intravascular large B cell lymphoma, the patient received rituximab-based chemotherapy under close follow-up. The Korean Society of Pathologists and the Korean Society for Cytopathology 2020-09 2020-08-13 /pmc/articles/PMC7483029/ /pubmed/32781826 http://dx.doi.org/10.4132/jptm.2020.06.18 Text en © 2020 The Korean Society of Pathologists/The Korean Society for Cytopathology This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Study Kim, Moonsik Chung, Haerim Yang, Woo Ick Jeong, Hyeon Joo Renal intravascular large B cell lymphoma: the first case report in Korea and a review of the literature |
title | Renal intravascular large B cell lymphoma: the first case report in Korea and a review of the literature |
title_full | Renal intravascular large B cell lymphoma: the first case report in Korea and a review of the literature |
title_fullStr | Renal intravascular large B cell lymphoma: the first case report in Korea and a review of the literature |
title_full_unstemmed | Renal intravascular large B cell lymphoma: the first case report in Korea and a review of the literature |
title_short | Renal intravascular large B cell lymphoma: the first case report in Korea and a review of the literature |
title_sort | renal intravascular large b cell lymphoma: the first case report in korea and a review of the literature |
topic | Case Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483029/ https://www.ncbi.nlm.nih.gov/pubmed/32781826 http://dx.doi.org/10.4132/jptm.2020.06.18 |
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