Pooling samples: a testing option for SARS-CoV-2 during a supply shortage

Pooling of 1 positive sample with up to 5 negative samples prior to testing with the Cepheid GenXpert SARS-CoV-2 assay did not adversely impact detection of positive samples. At our current prevalence of 2%, it could save up to 70% of the test kits.

Detalles Bibliográficos
Autores principales: Salimnia, Hossein, Mitchell, Robert, Gundel, Angela, Cambell, Alicia, Gammou, Fadi, Chopra, Teena, Fairfax, Marilynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2021
Materias:
Virology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483063/
https://www.ncbi.nlm.nih.gov/pubmed/33190092
http://dx.doi.org/10.1016/j.diagmicrobio.2020.115205
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author Salimnia, Hossein
Mitchell, Robert
Gundel, Angela
Cambell, Alicia
Gammou, Fadi
Chopra, Teena
Fairfax, Marilynn
author_facet Salimnia, Hossein
Mitchell, Robert
Gundel, Angela
Cambell, Alicia
Gammou, Fadi
Chopra, Teena
Fairfax, Marilynn
author_sort Salimnia, Hossein
collection PubMed
description Pooling of 1 positive sample with up to 5 negative samples prior to testing with the Cepheid GenXpert SARS-CoV-2 assay did not adversely impact detection of positive samples. At our current prevalence of 2%, it could save up to 70% of the test kits.
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spelling pubmed-74830632020-09-11 Pooling samples: a testing option for SARS-CoV-2 during a supply shortage Salimnia, Hossein Mitchell, Robert Gundel, Angela Cambell, Alicia Gammou, Fadi Chopra, Teena Fairfax, Marilynn Diagn Microbiol Infect Dis Virology Pooling of 1 positive sample with up to 5 negative samples prior to testing with the Cepheid GenXpert SARS-CoV-2 assay did not adversely impact detection of positive samples. At our current prevalence of 2%, it could save up to 70% of the test kits. Published by Elsevier Inc. 2021-01 2020-09-11 /pmc/articles/PMC7483063/ /pubmed/33190092 http://dx.doi.org/10.1016/j.diagmicrobio.2020.115205 Text en © 2020 Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Virology
Salimnia, Hossein
Mitchell, Robert
Gundel, Angela
Cambell, Alicia
Gammou, Fadi
Chopra, Teena
Fairfax, Marilynn
Pooling samples: a testing option for SARS-CoV-2 during a supply shortage
title Pooling samples: a testing option for SARS-CoV-2 during a supply shortage
title_full Pooling samples: a testing option for SARS-CoV-2 during a supply shortage
title_fullStr Pooling samples: a testing option for SARS-CoV-2 during a supply shortage
title_full_unstemmed Pooling samples: a testing option for SARS-CoV-2 during a supply shortage
title_short Pooling samples: a testing option for SARS-CoV-2 during a supply shortage
title_sort pooling samples: a testing option for sars-cov-2 during a supply shortage
topic Virology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483063/
https://www.ncbi.nlm.nih.gov/pubmed/33190092
http://dx.doi.org/10.1016/j.diagmicrobio.2020.115205
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