Low-Frequency Intrapulmonary Percussive Ventilation Increases Aerosol Penetration in a 2-Compartment Physical Model of Fibrotic Lung Disease

In patients with fibrotic pulmonary disease such as idiopathic pulmonary fibrosis (IPF), inhaled aerosols deposit mostly in the less affected region of the lungs, resulting in suboptimal pharmacokinetics of airway-delivered treatments. Refinement of aerosol delivery technique requires new models to...

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Detalles Bibliográficos
Autores principales: Le Guellec, Sandrine, Allimonnier, Laurine, Heuzé-Vourc’h, Nathalie, Cabrera, Maria, Ossant, Frédéric, Pourchez, Jérémie, Vecellio, Laurent, Plantier, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483496/
https://www.ncbi.nlm.nih.gov/pubmed/32984287
http://dx.doi.org/10.3389/fbioe.2020.01022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483496/
https://www.ncbi.nlm.nih.gov/pubmed/32984287
http://dx.doi.org/10.3389/fbioe.2020.01022

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