Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis

Traumatic brain injury (TBI) is a leading global cause of death and disability. Here we demonstrate in an experimental mouse model of TBI that mild forms of brain trauma cause severe deficits in meningeal lymphatic drainage that begin within hours and last out to at least one month post-injury. To i...

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Detalles Bibliográficos
Autores principales: Bolte, Ashley C., Dutta, Arun B., Hurt, Mariah E., Smirnov, Igor, Kovacs, Michael A., McKee, Celia A., Ennerfelt, Hannah E., Shapiro, Daniel, Nguyen, Bao H., Frost, Elizabeth L., Lammert, Catherine R., Kipnis, Jonathan, Lukens, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483525/
https://www.ncbi.nlm.nih.gov/pubmed/32913280
http://dx.doi.org/10.1038/s41467-020-18113-4

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