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A pan-cancer assessment of alterations of the kinase domain of ULK1, an upstream regulator of autophagy
Autophagy is a key clearance process to recycle damaged cellular components. One important upstream regulator of autophagy is ULK1 kinase. Several three-dimensional structures of the ULK1 catalytic domain are available, but a comprehensive study, including molecular dynamics, is missing. Also, an ex...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483646/ https://www.ncbi.nlm.nih.gov/pubmed/32913252 http://dx.doi.org/10.1038/s41598-020-71527-4 |