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Malakoplakia, a malignant mimic

Malakoplakia is a chronic inflammatory condition that affects multiple systems, most commonly the urogenital tract. Its clinical presentation is often non-specific, but is typically characterized by recurrent urinary tract infections and haematuria. We report a rare case of intravesical malakoplakia...

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Detalles Bibliográficos
Autores principales: Parkin, Cameron James, Acland, George, Sulaiman, Ban, Johnsun, Mark Louie, Latif, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bladder 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483825/
https://www.ncbi.nlm.nih.gov/pubmed/32934968
http://dx.doi.org/10.14440/bladder.2020.818
Descripción
Sumario:Malakoplakia is a chronic inflammatory condition that affects multiple systems, most commonly the urogenital tract. Its clinical presentation is often non-specific, but is typically characterized by recurrent urinary tract infections and haematuria. We report a rare case of intravesical malakoplakia mimicking an aggressive transitional cell carcinoma both in its clinical presentation and in its macroscopic appearance on cystoscopy in an 82-year patient, the oldest reported case in the literature. Malakoplakia has been described in the literature as a benign disease process presenting typically in younger patients. This case demonstrates its ability to cause obstructive uropathy and affect elderly patients. Thus, this case serves as a reminder to consider malakoplakia as a differential in the evaluation of suspected bladder malignancy in patients of all ages.