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Malakoplakia, a malignant mimic

Malakoplakia is a chronic inflammatory condition that affects multiple systems, most commonly the urogenital tract. Its clinical presentation is often non-specific, but is typically characterized by recurrent urinary tract infections and haematuria. We report a rare case of intravesical malakoplakia...

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Autores principales: Parkin, Cameron James, Acland, George, Sulaiman, Ban, Johnsun, Mark Louie, Latif, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bladder 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483825/
https://www.ncbi.nlm.nih.gov/pubmed/32934968
http://dx.doi.org/10.14440/bladder.2020.818
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author Parkin, Cameron James
Acland, George
Sulaiman, Ban
Johnsun, Mark Louie
Latif, Edward
author_facet Parkin, Cameron James
Acland, George
Sulaiman, Ban
Johnsun, Mark Louie
Latif, Edward
author_sort Parkin, Cameron James
collection PubMed
description Malakoplakia is a chronic inflammatory condition that affects multiple systems, most commonly the urogenital tract. Its clinical presentation is often non-specific, but is typically characterized by recurrent urinary tract infections and haematuria. We report a rare case of intravesical malakoplakia mimicking an aggressive transitional cell carcinoma both in its clinical presentation and in its macroscopic appearance on cystoscopy in an 82-year patient, the oldest reported case in the literature. Malakoplakia has been described in the literature as a benign disease process presenting typically in younger patients. This case demonstrates its ability to cause obstructive uropathy and affect elderly patients. Thus, this case serves as a reminder to consider malakoplakia as a differential in the evaluation of suspected bladder malignancy in patients of all ages.
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spelling pubmed-74838252020-09-14 Malakoplakia, a malignant mimic Parkin, Cameron James Acland, George Sulaiman, Ban Johnsun, Mark Louie Latif, Edward Bladder (San Franc) Case Report Malakoplakia is a chronic inflammatory condition that affects multiple systems, most commonly the urogenital tract. Its clinical presentation is often non-specific, but is typically characterized by recurrent urinary tract infections and haematuria. We report a rare case of intravesical malakoplakia mimicking an aggressive transitional cell carcinoma both in its clinical presentation and in its macroscopic appearance on cystoscopy in an 82-year patient, the oldest reported case in the literature. Malakoplakia has been described in the literature as a benign disease process presenting typically in younger patients. This case demonstrates its ability to cause obstructive uropathy and affect elderly patients. Thus, this case serves as a reminder to consider malakoplakia as a differential in the evaluation of suspected bladder malignancy in patients of all ages. Bladder 2020-09-02 /pmc/articles/PMC7483825/ /pubmed/32934968 http://dx.doi.org/10.14440/bladder.2020.818 Text en © 2013-2020, Bladder, All rights reserved. http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License: http://creativecommons.org/licenses/by-nc-sa/4.0
spellingShingle Case Report
Parkin, Cameron James
Acland, George
Sulaiman, Ban
Johnsun, Mark Louie
Latif, Edward
Malakoplakia, a malignant mimic
title Malakoplakia, a malignant mimic
title_full Malakoplakia, a malignant mimic
title_fullStr Malakoplakia, a malignant mimic
title_full_unstemmed Malakoplakia, a malignant mimic
title_short Malakoplakia, a malignant mimic
title_sort malakoplakia, a malignant mimic
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483825/
https://www.ncbi.nlm.nih.gov/pubmed/32934968
http://dx.doi.org/10.14440/bladder.2020.818
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