Cargando…

Immunosuppression Has Long-Lasting Effects on Circulating Follicular Regulatory T Cells in Kidney Transplant Recipients

Background: FoxP3(+) follicular regulatory T cells (Tfr) have been identified as the cell population controlling T follicular helper (Tfh) cells and B cells which, are both involved in effector immune responses against transplanted tissue. Methods: To understand the biology of Tfr cells in kidney tr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Niu, Qian, Mendoza Rojas, Aleixandra, Dieterich, Marjolein, Roelen, Dave L., Clahsen-van Groningen, Marian C., Wang, Lanlan, van Gelder, Teun, Hesselink, Dennis A., van Besouw, Nicole M., Baan, Carla C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483930/ https://www.ncbi.nlm.nih.gov/pubmed/32983131 http://dx.doi.org/10.3389/fimmu.2020.01972

Ejemplares similares

High Tacrolimus Intrapatient Variability and Subtherapeutic Immunosuppression are Associated With Adverse Kidney Transplant Outcomes
por: Mendoza Rojas, Aleixandra, et al.
Publicado: (2022)

Alloreactive T cells to Assess Acute Rejection Risk in Kidney Transplant Recipients
por: Mendoza Rojas, Aleixandra, et al.
Publicado: (2023)

Natural Antibodies and Alloreactive T Cells Long after Kidney Transplantation
por: van Besouw, Nicole M., et al.
Publicado: (2021)

Pre-transplant donor-reactive IL-21 producing T cells as a tool to identify an increased risk for acute rejection
por: Mendoza Rojas, Aleixandra, et al.
Publicado: (2021)

The role of follicular T helper cells in the humoral alloimmune response after clinical organ transplantation
por: van Besouw, Nicole M., et al.
Publicado: (2019)

The Number of Donor-Specific IL-21 Producing Cells Before and After Transplantation Predicts Kidney Graft Rejection
por: van Besouw, Nicole M., et al.
Publicado: (2019)

Tacrolimus intra-patient variability is not associated with chronic active antibody mediated rejection
por: Sablik, Kasia A., et al.
Publicado: (2018)

Belatacept Does Not Inhibit Follicular T Cell-Dependent B-Cell Differentiation in Kidney Transplantation
por: de Graav, Gretchen N., et al.
Publicado: (2017)

Avoiding Tacrolimus Underexposure and Overexposure with a Dosing Algorithm for Renal Transplant Recipients: A Single Arm Prospective Intervention Trial
por: Francke, Marith I., et al.
Publicado: (2021)

Immune Subsets From Ficoll Density Gradient Separation in Kidney Transplant Recipients
por: Udomkarnjananun, Suwasin, et al.
Publicado: (2022)

The Efficacy of Rabbit Anti-Thymocyte Globulin for Acute Kidney Transplant Rejection in Patients Using Calcineurin Inhibitor and Mycophenolate Mofetil-Based Immunosuppressive Therapy
por: van der Zwan, Marieke, et al.
Publicado: (2018)

T Follicular Helper Cells As a New Target for Immunosuppressive Therapies
por: Yan, Lin, et al.
Publicado: (2017)

Combining Sorafenib and Immunosuppression in Liver Transplant Recipients with Hepatocellular Carcinoma
por: Hussaarts, Koen G. A. M., et al.
Publicado: (2021)

Characterization of donor and recipient CD8+ tissue-resident memory T cells in transplant nephrectomies
por: de Leur, Kitty, et al.
Publicado: (2019)

Comparison of Alemtuzumab and Anti-thymocyte Globulin Treatment for Acute Kidney Allograft Rejection
por: van der Zwan, Marieke, et al.
Publicado: (2020)

Review of the Clinical Pharmacokinetics and Pharmacodynamics of Alemtuzumab and Its Use in Kidney Transplantation
por: van der Zwan, Marieke, et al.
Publicado: (2017)

Analysis of NFATc1 amplification in T cells for pharmacodynamic monitoring of tacrolimus in kidney transplant recipients
por: Kannegieter, Nynke M., et al.
Publicado: (2018)

Oxalate deposition in renal allograft biopsies within 3 months after transplantation is associated with allograft dysfunction
por: Snijders, Malou L. H., et al.
Publicado: (2019)

Monitoring the tacrolimus concentration in peripheral blood mononuclear cells of kidney transplant recipients
por: Francke, Marith I., et al.
Publicado: (2020)

Tacrolimus Monotherapy is Safe in Immunologically Low-Risk Kidney Transplant Recipients: A Randomized-Controlled Pilot Study
por: de Weerd, Annelies E., et al.
Publicado: (2022)

Costimulation Blockade in Kidney Transplant Recipients
por: van der Zwan, Marieke, et al.
Publicado: (2019)

Clinical and Molecular Profiling to Develop a Potential Prediction Model for the Response to Alemtuzumab Therapy for Acute Kidney Transplant Rejection
por: Hullegie‐Peelen, Daphne M., et al.
Publicado: (2022)

Circulating cell-free nucleosomes as biomarker for kidney transplant rejection: a pilot study
por: Verhoeven, Jeroen G. H. P., et al.
Publicado: (2021)

Cholesterol Embolization Syndrome After Kidney Transplantation: A Case Series and Systematic Review
por: Francke, Marith I., et al.
Publicado: (2021)

Mast Cells in Kidney Transplant Biopsies With Borderline T Cell-mediated Rejection and Their Relation to Chronicity
por: Varol, Hilal, et al.
Publicado: (2023)

The Biological Effects of IL-21 Signaling on B-Cell-Mediated Responses in Organ Transplantation
por: Wu, Yongkang, et al.
Publicado: (2016)

Down-Regulation of Surface CD28 under Belatacept Treatment: An Escape Mechanism for Antigen-Reactive T-Cells
por: de Graav, Gretchen N., et al.
Publicado: (2016)

Overweight Kidney Transplant Recipients Are at Risk of Being Overdosed Following Standard Bodyweight-Based Tacrolimus Starting Dose
por: Andrews, Louise M., et al.
Publicado: (2017)

Immunomics of Renal Allograft Acute T Cell-Mediated Rejection Biopsies of Tacrolimus- and Belatacept-Treated Patients
por: van der Zwan, Marieke, et al.
Publicado: (2018)

Differential T Cell Signaling Pathway Activation by Tacrolimus and Belatacept after Kidney Transplantation: Post Hoc Analysis of a Randomised-Controlled Trial
por: Kannegieter, Nynke M., et al.
Publicado: (2017)

Diagnostic Potential of Minimally Invasive Biomarkers: A Biopsy-centered Viewpoint From the Banff Minimally Invasive Diagnostics Working Group
por: Huang, Edmund, et al.
Publicado: (2022)

The mast cell: A Janus in kidney transplants
por: van der Elst, G., et al.
Publicado: (2023)

Corrigendum: The mast cell: A Janus in kidney transplants
por: van der Elst, G., et al.
Publicado: (2023)

Determining the therapeutic range for ribavirin in transplant recipients with chronic hepatitis E virus infection
por: Mulder, Midas B., et al.
Publicado: (2020)

Causes of Kidney Graft Failure in a Cohort of Recipients With a Very Long-Time Follow-Up After Transplantation
por: Betjes, Michiel G. H., et al.
Publicado: (2022)

Adipose Tissue-Derived Mesenchymal Stem Cells Have a Heterogenic Cytokine Secretion Profile
por: Wu, Yongkang, et al.
Publicado: (2017)

Response: Commentary: Belatacept Does Not Inhibit Follicular T Cell-Dependent B-Cell Differentiation in Kidney Transplantation
por: Baan, Carla C., et al.
Publicado: (2018)

A randomized crossover study comparing different tacrolimus formulations to reduce intrapatient variability in tacrolimus exposure in kidney transplant recipients
por: Bunthof, Kim L. W., et al.
Publicado: (2021)

The Effect of Tacrolimus and Mycophenolic Acid on CD14+ Monocyte Activation and Function
por: Kannegieter, Nynke M., et al.
Publicado: (2017)

A new method to calculate intra‐patient variability in tacrolimus concentrations
por: van Gelder, Teun
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_sg6sfpd1gnbbuqoja1lfh2f9ju