Cargando…
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
The TRPA1 ion channel is expressed by primary afferent nerve fibers, where it functions as a low threshold sensor for structurally diverse electrophilic irritants ranging from small volatile environmental toxicants to endogenous algogenic lipids(1). TRPA1 is also a ‘receptor-operated’ channel whose...
Autores principales: | Zhao, Jianhua, Lin King, John V., Paulsen, Candice E., Cheng, Yifan, Julius, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483980/ https://www.ncbi.nlm.nih.gov/pubmed/32641835 http://dx.doi.org/10.1038/s41586-020-2480-9 |
Ejemplares similares
-
Structure of the TRPA1 ion channel suggests regulatory mechanisms
por: Paulsen, Candice E., et al.
Publicado: (2015) -
The irritant receptor TRPA1 mediates the mosquito repellent effect of catnip
por: Melo, Nadia, et al.
Publicado: (2021) -
Methylglyoxal Evokes Pain by Stimulating TRPA1
por: Andersson, David A., et al.
Publicado: (2013) -
Correction: Methylglyoxal Evokes Pain by Stimulating TRPA1
por: Andersson, David A., et al.
Publicado: (2013) -
Weakly acidic, but strongly irritating: TRPA1 and the activation of nociceptors by cytoplasmic acidification
por: Garrity, Paul A.
Publicado: (2011)