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Improvement of cryo-EM maps by density modification
A density modification procedure for improving maps from single-particle electron cryo-microscopy is presented. The theoretical basis of the method is identical to that of maximum-likelihood density modification, previously used to improve maps from macromolecular X-ray crystallography. Key differen...
Autores principales: | Terwilliger, Thomas C., Ludtke, Steven J., Read, Randy J., Adams, Paul D., Afonine, Pavel V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484085/ https://www.ncbi.nlm.nih.gov/pubmed/32807957 http://dx.doi.org/10.1038/s41592-020-0914-9 |
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