Prognostic gene expression signature for high-grade serous ovarian cancer

BACKGROUND: Median overall survival (OS) for women with high-grade serous ovarian cancer (HGSOC) is ~4 years, yet survival varies widely between patients. There are no well-established, gene expression signatures associated with prognosis. The aim of this study was to develop a robust prognostic sig...

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Autores principales: Millstein, J., Budden, T., Goode, E. L., Anglesio, M. S., Talhouk, A., Intermaggio, M. P., Leong, H. S., Chen, S., Elatre, W., Gilks, B., Nazeran, T., Volchek, M., Bentley, R. C., Wang, C., Chiu, D. S., Kommoss, S., Leung, S. C. Y., Senz, J., Lum, A., Chow, V., Sudderuddin, H., Mackenzie, R., George, J., Fereday, S., Hendley, J., Traficante, N., Steed, H., Koziak, J. M., Köbel, M., McNeish, I. A., Goranova, T., Ennis, D., Macintyre, G., Silva De Silva, D., Ramón y Cajal, T., García-Donas, J., Hernando Polo, S., Rodriguez, G. C., Cushing-Haugen, K. L., Harris, H. R., Greene, C. S., Zelaya, R. A., Behrens, S., Fortner, R. T., Sinn, P., Herpel, E., Lester, J., Lubiński, J., Oszurek, O., Tołoczko, A., Cybulski, C., Menkiszak, J., Pearce, C. L., Pike, M. C., Tseng, C., Alsop, J., Rhenius, V., Song, H., Jimenez-Linan, M., Piskorz, A. M., Gentry-Maharaj, A., Karpinskyj, C., Widschwendter, M., Singh, N., Kennedy, C. J., Sharma, R., Harnett, P. R., Gao, B., Johnatty, S. E., Sayer, R., Boros, J., Winham, S. J., Keeney, G. L., Kaufmann, S. H., Larson, M. C., Luk, H., Hernandez, B. Y., Thompson, P. J., Wilkens, L. R., Carney, M. E., Trabert, B., Lissowska, J., Brinton, L., Sherman, M. E., Bodelon, C., Hinsley, S., Lewsley, L. A., Glasspool, R., Banerjee, S. N., Stronach, E. A., Haluska, P., Ray-Coquard, I., Mahner, S., Winterhoff, B., Slamon, D., Levine, D. A., Kelemen, L. E., Benitez, J., Chang-Claude, J., Gronwald, J., Wu, A. H., Menon, U., Goodman, M. T., Schildkraut, J. M., Wentzensen, N., Brown, R., Berchuck, A., Chenevix-Trench, G., deFazio, A., Gayther, S. A., García, M. J., Henderson, M. J., Rossing, M. A., Beeghly-Fadiel, A., Fasching, P. A., Orsulic, S., Karlan, B. Y., Konecny, G. E., Huntsman, D. G., Bowtell, D. D., Brenton, J. D., Doherty, J. A., Pharoah, P. D. P., Ramus, S. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484370/
https://www.ncbi.nlm.nih.gov/pubmed/32473302
http://dx.doi.org/10.1016/j.annonc.2020.05.019

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